{"title":"May 2026 20% Discount Collection","description":"\u003cp\u003eMay 2026 20% Discount Collection\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/novaskin.care\/\"\u003eOur Website\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003ca href=\"https:\/\/campsite.bio\/novaskinmedidermik\" title=\"NovaSkin \u0026amp; MediDermik\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"brilliance-back-bar-kit","title":"Brilliance Back Bar kit 7 products (Hyperpigmentation)","description":"\u003cp\u003e\u003c!--StartFragment --\u003e\u003c\/p\u003e\n\u003cp class=\"pf0\"\u003e\u003cstrong\u003e\u003cspan class=\"cf0\"\u003e***Sold only to professionals in the beauty\/medical field***\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"pf0\"\u003e\u003cstrong\u003e\u003cspan class=\"cf0\"\u003eMake sure you provide your license number when placing your order in the \"Notes\" field or text it to 786-468-8671\"\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"pf0\"\u003e\u003cstrong\u003e\u003cspan class=\"cf0\"\u003eWe will cancel the order if license number is not provided.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003c!--EndFragment --\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eBrilliance Back Bar kit 7 products It includes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBrilliance Serum 1oz (30ml)\u003c\/li\u003e\n\u003cli\u003eLuminous Cream 4oz (120ml)\u003c\/li\u003e\n\u003cli\u003eNeutra Peel Solution 4oz (120ml)\u003c\/li\u003e\n\u003cli\u003ePre Peel Solution 4oz (120ml)\u003c\/li\u003e\n\u003cli\u003eBrilliance 50% Peel 2oz (60ml)\u003c\/li\u003e\n\u003cli\u003eTea Tree Cleanser 8oz (240ml)\u003c\/li\u003e\n\u003cli\u003eGreen Tea Nutri Toner 8oz (240ml)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/novaskin.care\/collections\/hyperpigmentation\"\u003eMelasma\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eDark Spots.\u003c\/li\u003e\n\u003cli\u003eAge Spots.\u003c\/li\u003e\n\u003cli\u003eLentigo, or any hyperpigmented skin.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eDeep Cleansing with Tea Tree Cleanser.\u003c\/li\u003e\n\u003cli\u003eMild Exfoliation with Exfoliating Scrub and Brilliance 7.5% Exfoliant.\u003c\/li\u003e\n\u003cli\u003eDegreasing or Defatting Step with Pre-Peel Solution.\u003c\/li\u003e\n\u003cli\u003eBrilliance 50% Peel Application with fan brush or gauze.\u003c\/li\u003e\n\u003cli\u003ePeeling Time: 1-2 minutes depending on the skin tolerance.\u003c\/li\u003e\n\u003cli\u003ePeel Neutralization \u0026amp; Removal with Neutra Peel Solution.\u003c\/li\u003e\n\u003cli\u003eTonification with Green Tea Nutri-Toner.\u003c\/li\u003e\n\u003cli\u003eTreatment serum application: Brilliance Serum.\u003c\/li\u003e\n\u003cli\u003eMask Application: Brilliance Peel Off Mask to alleviate redness and discomfort.\u003c\/li\u003e\n\u003cli\u003eMoisturizing Step with Luminous Cream.\u003c\/li\u003e\n\u003cli\u003eSun Protection application with RadiantShield.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eIngredients\u003c\/h2\u003e\n\u003cp\u003eBrilliance Back Bar kit 7 products It includes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBrilliance Serum 1oz (30ml)\u003c\/li\u003e\n\u003cli\u003eLuminous Cream 4oz (120ml)\u003c\/li\u003e\n\u003cli\u003eNeutra Peel Solution 4oz (120ml)\u003c\/li\u003e\n\u003cli\u003ePre Peel Solution 4oz (120ml)\u003c\/li\u003e\n\u003cli\u003eBrilliance 50% Peel 2oz (60ml)\u003c\/li\u003e\n\u003cli\u003eTea Tree Cleanser 8oz (240ml)\u003c\/li\u003e\n\u003cli\u003eGreen Tea Nutri Toner 8oz (240ml)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/campsite.bio\/novaskinmedidermik\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eBrilliance Back Bar kit\u003c\/h2\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":45234937626854,"sku":"nbrilliancebbkit","price":156.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/nbrilliancebbkit2.webp?v=1764106741"},{"product_id":"brilliance-50-peel-kojic","title":"Brilliance 50% Peel 2oz","description":"\u003cp\u003e\u003c!--StartFragment --\u003e\u003c\/p\u003e\n\u003cp class=\"pf0\"\u003e\u003cstrong\u003e\u003cspan class=\"cf0\"\u003e***Sold only to professionals in the beauty\/medical field***\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"pf0\"\u003e\u003cstrong\u003e\u003cspan class=\"cf0\"\u003eMake sure you provide your license number when placing your order in the \"Notes\" field or text it to 786-468-8671\"\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"pf0\"\u003e\u003cstrong\u003e\u003cspan class=\"cf0\"\u003eWe will cancel the order if license number is not provided.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003c!--EndFragment --\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eBrilliance 50% Peel (AHA 50% with Kojic Acid) is an exfoliating and skin whitening masterpiece that uses 3 of the most effective and natural alpha-hydroxy acids along with Kojic Acid to deliver a superior exfoliation and skin whitening experience.\u003c\/p\u003e\n\u003cp\u003eIn a soothing and skin nourishing gel. Peel indicated for hyperpigmented skin. Combines Glycolic Acid, Lactic Acid, Kojic Acid \u0026amp; Pyruvic Acid for effective exfoliation.\u003c\/p\u003e\n\u003cp\u003eExfoliates dead skin and removes toxins from the skin.\u003c\/p\u003e\n\u003cp\u003eAdded Kojic Acid for additional skin lightening properties for hyperpigmented areas.\u003c\/p\u003e\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/novaskin.care\/collections\/hyperpigmentation\"\u003eHyper Pigmented\u003c\/a\u003e skin such as melasma.\u003c\/li\u003e\n\u003cli\u003eChloasma.\u003c\/li\u003e\n\u003cli\u003ePIH.\u003c\/li\u003e\n\u003cli\u003eAge spots.\u003c\/li\u003e\n\u003cli\u003eLentigo.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt can also be used for any other skin type for the purpose of rejuvenation.\u003c\/p\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003eNot for sensitive skin. Always perform a patch test behind the ear to test sensitivity.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e Cleanse skin with Tea Tree Cleanser, degrease skin with Pre-Peel Solution, apply 2-3 ml of Peel to skin, leave on for 1-2 minutes depending on client's tolerance, then remove and neutralize acid with our NeutraPeel.\u003c\/li\u003e\n\u003cli\u003eApply Green Tea \u0026amp; Pomegranate NutriToner to restore pH to skin.\u003c\/li\u003e\n\u003cli\u003eApply respective Serum, use a Peel Off Mask to help penetrate the serum, leave mask for 15 minutes, remove mask, apply respective Moisturizer Cream then finish with our Antiaging Cream SPF 30.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eIngredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eGlycolic Acid.\u003c\/li\u003e\n\u003cli\u003eLactic Acid Kojic.\u003c\/li\u003e\n\u003cli\u003eAcid Pyruvic Acid.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/campsite.bio\/novaskinmedidermik\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eBrilliance 50%\u003c\/h2\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":45234939068646,"sku":"nbrill502oz","price":36.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/nbrill502oz_2.webp?v=1764092097"},{"product_id":"brilliance-peel-off-mask","title":"Brilliance Peel-Off Mask 20oz","description":"\u003cp\u003e\u003cstrong\u003eBrilliance Peel-Off Mask\u003c\/strong\u003e is an alginate-based mask with gamma (γ) oryzanol obtained from rice bran, vitamin C, and plant extracts from Yarrow plant, Lady Mantle, Lemon Balm, Cowslip, and Speedwell that provides a powerful UV rays protective effect that improves uneven skin tone and antioxidant effect against free radicals.  The brightening effect helps correct hyperpigmentation and inhibits melanogenesis. (Hydroquinone free product).\u003c\/p\u003e\n\u003cp\u003eIt combat free radicals and inhibit melanin synthesis, preventing dark spots. Alfa Oryzanol is a melanogenesis regulator that reduces gene expression and inhibits tyrosinase.\u003c\/p\u003e\n\u003cp\u003eVitamin C also captures free radicals, known for causing skin aging and damage.\u003c\/p\u003e\n\u003cp\u003eThis natural mask, made from a Laminaria seaweed complex alginate, contains no preservatives and has hypoallergenic qualities suitable for all skin types.\u003c\/p\u003e\n\u003cp\u003eIt creates an ideal environment for professional facial treatments by freshening and tightening skin while diffusing active ingredients from serums.\u003c\/p\u003e\n\u003cp\u003eThe peel off feature provides necessary occlusion to enhance the penetration of our serums' active ingredients.\u003c\/p\u003e\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/novaskin.care\/collections\/hyperpigmentation\"\u003eAge Spots.\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003eUneven Tone.\u003c\/li\u003e\n\u003cli\u003eAnti-Oxidant effect.\u003c\/li\u003e\n\u003cli\u003eSoothing effect.\u003c\/li\u003e\n\u003cli\u003eCalming effect.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOcclusive Effect especially after treatments such as chemical peels, micro-needling, microdermabrasion, laser treatment, extractions or any treatment that leaves the client's skin irritated.\u003c\/p\u003e\n\u003cp\u003ePeel Off Masks are very suitable for helping soothe and calm client's skin during a facial and help penetrate serums because of its occlusion effect.\u003c\/p\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003e(Ratio 1:2) Use 79 grams (1\/3 cup) of powder mask for 158 grams (2\/3 cup) of water.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePour water rapidly on the powder.\u003c\/li\u003e\n\u003cli\u003eMix vigorously approximately 1 minute until a homogeneous paste is obtained. Apply the mask immediately to whole face (except over nostrils) if client is comfortable or just avoid eye area and mouth.\u003c\/li\u003e\n\u003cli\u003eThe mask sets in about 6 minutes.\u003c\/li\u003e\n\u003cli\u003eLeave mask on at least 15 minutes.\u003c\/li\u003e\n\u003cli\u003eThen remove in one piece.\u003c\/li\u003e\n\u003cli\u003eMoistening the edges of the mask around the face helps the removal leaving less traces.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOur traditional alginate based peel off masks are manufactured in France with the highest standards and purity. \u003c\/p\u003e\n\u003cp\u003eOur alginate based peel off masks can yield up to 20 facial masks depending on the area you want to treat.\u003c\/p\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDiatomaceous Earth\u003c\/li\u003e\n\u003cli\u003eSepiolite\u003c\/li\u003e\n\u003cli\u003eOryza (Rice) Sativa Powder\u003c\/li\u003e\n\u003cli\u003eAlgin \u003c\/li\u003e\n\u003cli\u003eVitamin C\u003c\/li\u003e\n\u003cli\u003eAchillea Millefolium Flower Extract\u003c\/li\u003e\n\u003cli\u003eAlchemilla Vulgaris Flower Extract\u003c\/li\u003e\n\u003cli\u003eMalva Sylvestris Flower Extract\u003c\/li\u003e\n\u003cli\u003eMelissa Officinalis Leaf Extract\u003c\/li\u003e\n\u003cli\u003eMentha Piperita Leaf Extract\u003c\/li\u003e\n\u003cli\u003ePrimula Veris Flower Extract\u003c\/li\u003e\n\u003cli\u003eVeronica Officinalis Flower Extract\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/campsite.bio\/novaskinmedidermik\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eBrilliance Peel-Off Mask\u003c\/h2\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":45234939625702,"sku":"nbrightmask","price":34.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/Brilliance_Peel_Off_Mask_20oz.webp?v=1764016404"},{"product_id":"brilliance-7-5-exfoliant","title":"Brilliance 7.5% Exfoliant (AHA 7.5% with Kojic Acid) 1.7oz","description":"\u003cp\u003eBrilliance 7.5% Exfoliant is a combination of alpha-hydroxy acids, Glycolic Acid, Pyruvic Acid, Kojic Acid, and Lactic Acid for the treatment of hyper pigmentation such as melasma, chloasma, age spots, PIH, and lentigo.\u003c\/p\u003e\n\u003cp\u003eOur peel provides high quality exfoliation in a nourishing and penetrating gel.\u003c\/p\u003e\n\u003cp\u003eThis provides a more thorough and effective exfoliation experience.\u003c\/p\u003e\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/novaskin.care\/collections\/hyperpigmentation\"\u003eHyper Pigmented\u003c\/a\u003e skin such as melasma.\u003c\/li\u003e\n\u003cli\u003eChloasma. \u003c\/li\u003e\n\u003cli\u003ePIH age spots.\u003c\/li\u003e\n\u003cli\u003eLentigo, and intimate bleaching. \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIt can also be used for any other skin type for the purpose of rejuvenation.\u003c\/p\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003eA sensitivity test is recommended behind the ear before using this exfoliant.\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eApply 2 or 3 times a week at night after cleasing.\u003c\/li\u003e\n\u003cli\u003eApply a thin layer and leave on for about 3 minutes, then remove with water.\u003c\/li\u003e\n\u003cli\u003eFollow with toner, then apply the serum.\u003c\/li\u003e\n\u003cli\u003eFinally apply the moisturizing cream.\u003c\/li\u003e\n\u003cli\u003eMost chemical exfoliants are not recommended for sensitive skin.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eIngredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eGlycolic Acid.\u003c\/li\u003e\n\u003cli\u003eLactic Acid.\u003c\/li\u003e\n\u003cli\u003eKojic Acid Pyruvic Acid.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/campsite.bio\/novaskinmedidermik\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eBrilliance 7.5%\u003c\/h2\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":45234940346598,"sku":"nbrill7517oz","price":43.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/nbrilliance7517oz_2.webp?v=1764093446"},{"product_id":"brilliance-whitening-serum","title":"Brilliance Whitening Serum 1oz","description":"\u003cp\u003eBrilliance Whitening Serum is a unique serum formulated as a safe and natural alternative to hydroquinone with ingredients (alpha arbutin, kojic acid, licorice extract, bearberry \u0026amp; mulberry extract) that are proven safe and effective in lightening and brightening skin discolorations, pigmentation problems, and age spots.\u003c\/p\u003e\n\u003cp\u003eIt is enhanced with natural moisturizing factors (urea and lactic acid) for increased skin hydration.\u003c\/p\u003e\n\u003cp\u003eIt is a product used on the face that lightens the skin giving an appearance of lighter-younger looking skin.\u003c\/p\u003e\n\u003cp\u003eOur Brilliance Serum contains the alpha version of arbutin which is the more active and stable form of the molecule that is widely used as an alternative to the carcinogenic compound, hydroquinone.\u003c\/p\u003e\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/novaskin.care\/collections\/hyperpigmentation\"\u003eMelasma\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003eChloasma.\u003c\/li\u003e\n\u003cli\u003eAge Spots.\u003c\/li\u003e\n\u003cli\u003eLentigo, and Dark Blemishes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003eApply once or twice daily to facial area.\u003c\/p\u003e\n\u003cp\u003eThis product could be more effective if applied after a mild exfoliation with microdermabrasion, scrub or our Brilliance 7.5% Exfoliant.\u003c\/p\u003e\n\u003cp\u003eApply sunscreen during the day while using this product\u003c\/p\u003e\n\u003ch2\u003eIngredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAlpha Arbutin Kojic Acid\u003c\/li\u003e\n\u003cli\u003eLactic Acid.\u003c\/li\u003e\n\u003cli\u003e Glycyrrhiza Glabra (Licorice) Extract.\u003c\/li\u003e\n\u003cli\u003eMorus alba (Mulberry) Leaf Extract.\u003c\/li\u003e\n\u003cli\u003eUva Ursi (Bearberry) Extract.\u003c\/li\u003e\n\u003cli\u003eResveratrol Urea Niacinamide.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/campsite.bio\/novaskinmedidermik\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eBrilliance Whitening Serum\u003c\/h2\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":45234940510438,"sku":"nbrillserum","price":54.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/nbrillserum2.webp?v=1764093757"},{"product_id":"tranexamic-1500-dermik","title":"Tranexamic 1500 Dermik Lyophilized","description":"\u003cp\u003eTranexamic 1500 Dermik helps improve the appearance of blemished skin with dark spots.\u003c\/p\u003e\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMelasma.\u003c\/li\u003e\n\u003cli\u003eChloasma.\u003c\/li\u003e\n\u003cli\u003eGeneral Dyschromias and Post Inflammatory Hyper Pigmentation (PIH).\u003c\/li\u003e\n\u003cli\u003eHair Loss and Damage.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003eTranexamic 1500 IU can be applied by means of:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVirtual Mesotherapy with Electroporation.\u003c\/li\u003e\n\u003cli\u003eIontophoresis (Galvanic Current).\u003c\/li\u003e\n\u003cli\u003eMicroNeedling with dermapen or dermarollers\u003c\/li\u003e\n\u003cli\u003eTopical Application Post-Peeling\u003c\/li\u003e\n\u003cli\u003eTopical Application Post-Microdermabrasion\u003c\/li\u003e\n\u003cli\u003eTopical Application with massage\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eEach vial contains 1,500 IU of the active ingredient that can be reconstituted with 10ml of sterile NaCl 0.9% solution.\u003c\/p\u003e\n\u003ch2\u003eIngredients\u003c\/h2\u003e\n\u003cp\u003eActive Ingredients:\u003c\/p\u003e\n\u003cp\u003eTranexamic Acid (\u003ca href=\"https:\/\/novaskin.care\/collections\/lyophilized-line\"\u003elyophilized\u003c\/a\u003e) 1,500 IU in each vial.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eTranexamic 1500\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/campsite.bio\/novaskinmedidermik\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/a\u003e\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":45234948243686,"sku":"mktrane","price":219.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/Tranexamic_1500_Dermik_5_vials_Lyophilized_1_500_IU_-_Nova_Skin_Medidermik.webp?v=1764053177"},{"product_id":"glutathione-1500-dermik","title":"Glutathione 1500 Dermik  Lyophilized","description":"\u003cp data-start=\"806\" data-end=\"1086\"\u003e\u003cstrong data-start=\"806\" data-end=\"853\"\u003eGlutathione 1500 Dermik (1,500 IU per vial)\u003c\/strong\u003e\u003cbr data-start=\"853\" data-end=\"856\"\u003eA professional antioxidant formula designed to support a brighter, more even-looking complexion. Each vial contains lyophilized Glutathione, a powerful ingredient that revitalize the skin’s appearance and promote radiance.\u003c\/p\u003e\n\u003cp data-start=\"1088\" data-end=\"1102\"\u003e\u003cstrong data-start=\"1088\" data-end=\"1100\"\u003eBenefits\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"1105\" data-end=\"1170\"\u003eImprove the look of uneven tone and visible discoloration\u003c\/li\u003e\n\u003cli data-start=\"1173\" data-end=\"1219\"\u003ePromotes a brighter, more radiant complexion\u003c\/li\u003e\n\u003cli data-start=\"1222\" data-end=\"1283\"\u003eSupports the appearance of smoother, healthier-looking skin\u003c\/li\u003e\n\u003cli data-start=\"1286\" data-end=\"1356\"\u003eProvides antioxidant protection for refreshed, youthful-looking skin\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"1358\" data-end=\"1391\"\u003e\u003cstrong data-start=\"1358\" data-end=\"1389\"\u003eSuggested Professional Uses\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"1394\" data-end=\"1436\"\u003eVirtual Mesotherapy with Electroporation\u003c\/li\u003e\n\u003cli data-start=\"1439\" data-end=\"1473\"\u003eIontophoresis (Galvanic Current)\u003c\/li\u003e\n\u003cli data-start=\"1476\" data-end=\"1492\"\u003eRadiofrequency\u003c\/li\u003e\n\u003cli data-start=\"1495\" data-end=\"1537\"\u003eMicroneedling (dermapen or dermarollers)\u003c\/li\u003e\n\u003cli data-start=\"1540\" data-end=\"1597\"\u003eTopical application post-peel or post-microdermabrasion\u003c\/li\u003e\n\u003cli data-start=\"1600\" data-end=\"1626\"\u003eApplication with massage\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"1628\" data-end=\"1651\"\u003e\u003cstrong data-start=\"1628\" data-end=\"1649\"\u003eActive Ingredient\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"1654\" data-end=\"1699\"\u003eGlutathione (lyophilized) 1,500 IU per vial\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"1701\" data-end=\"1840\"\u003e\u003cstrong data-start=\"1701\" data-end=\"1714\"\u003ePackaging\u003c\/strong\u003e\u003cbr data-start=\"1714\" data-end=\"1717\"\u003eEach box contains vials that must be reconstituted with sterile NaCl 0.9% solution prior to use in professional settings.\u003c\/p\u003e\n\u003cp data-start=\"1842\" data-end=\"1877\"\u003e\u003cstrong data-start=\"1842\" data-end=\"1851\"\u003eBrand\u003c\/strong\u003e\u003cbr data-start=\"1851\" data-end=\"1854\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":45234948276454,"sku":"mkgluta1500","price":219.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/Glutathione_1500_Dermik_Lyophilized_1_500_IU_-_Nova_Skin_Medidermik.webp?v=1764049076"},{"product_id":"brilliance-exosome-dermik","title":"Brilliance Exosome Dermik","description":"\u003cp dir=\"ltr\"\u003e\u003cspan\u003e\u003cstrong\u003eBrilliance Exosome Dermik\u003c\/strong\u003e helps improve the appearance of hyperpigmented skin such as\u003c\/span\u003e\u003ca href=\"https:\/\/novaskin.care\/collections\/hyperpigmentation\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003edark spots\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e, age spots, PIH, uneven tone, lentigo, fleckless, and sunspots.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIt has more than 30 millions of exosomes.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003ePresentation\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e5 vials x 10ml (50ml)\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eIndications\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eAge, dark spots.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003ePIH.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eUneven tone.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eLentigo.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eFreckles.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eSun spots.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eHow to Use\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eBrilliance Exosome\u003c\/span\u003e\u003cspan\u003e can be applied by means of:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eElectroporation.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eIontophoresis (Galvanic Current).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eDermapen.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eTopical Application Post-Peeling\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eTopical Application Post-Microdermabrasion.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eTopical Application with massage.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eIngredients\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eAqua (Water)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eLactobacillus Extracellular Vesicles 4%.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eGalactomyces Extracellular Vesicles 6%.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eTranexamic Acid 2%.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eBrilliance Exosome Dermik\u003c\/span\u003e\u003cspan\u003e is designed to promote the brightening of the skin mediated by the following tranexamic acid mechanisms:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eTyrosinase Inhibition\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003ePlasmin Inhibition\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eModulation of Growth Factors\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eBlocking Effect on Melanin Transfer:\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eSynergistic Effect with Other Treatments\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eBrilliance Exosome Dermik\u003c\/span\u003e\u003cspan\u003e are tiny, membrane-bound extracellular vesicles secreted by cells that play a crucial role in cell-to-cell communication. Exosomes may contain various bioactive molecules, such as tranexamic acid, proteins, lipids, RNA, and DNA, which can influence cellular processes:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAnti-Aging Effect: Exosomes in general are believed to stimulate collagen production and improve skin elasticity, reducing the appearance of fine lines and wrinkles. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eRegeneration: They can promote the repair and regeneration of damaged skin cells, aiding in wound healing and improving skin texture.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eProtection against Inflammation: Exosomes may help protect against inflammation, making them useful for conditions like acne and rosacea.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eHydration and Brightening: By enhancing cellular communication, exosomes can contribute to improved skin hydration and a more even skin tone.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWhen applied to the skin, exosomes can penetrate the outer layers and deliver their cargo to skin cells, thereby modulating cellular functions and promoting skin health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eExosomes provide a highly effective and versatile delivery system for bioactive compounds, offering advantages in terms of biocompatibility, targeted delivery, protection of cargo, and efficient cellular uptake. These characteristics make them particularly valuable in both therapeutic and cosmetic applications.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWhen applied to the skin, exosomes can penetrate the outer layers and deliver their cargo to skin cells, thereby modulating cellular functions and promoting skin health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eExosomes are small extracellular vesicles, typically 30-150 nm in diameter, that are produced by a variety of cell types, including eukaryotic microorganisms such as Galactomyces candidum and Lactobacillus species. These vesicles play a key role in intercellular communication and can carry bioactive compounds such as tranexamic acid, epidermal growth factors, peptides, proteins, lipids, and genetic material. The production of exosomes from Galactomyces candidum or Lactobacillus involves several steps:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eBiogenesis: Exosome biogenesis in Galactomyces candidum, as in other cells, occurs through the endosomal pathway:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eEndocytosis: The cell membrane invaginates to form early endosomes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eMaturation: Early endosomes mature into late endosomes, also known as multivesicular bodies (MVBs). During this process, inward budding of the endosomal membrane occurs, resulting in the formation of intraluminal vesicles (ILVs) within the MVBs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eCargo Sorting: Specific bioactive compounds, peptides, proteins, lipids, and nucleic acids are selectively incorporated into these ILVs. The sorting mechanisms involve several protein complexes, including the endosomal sorting complexes required for transport (ESCRT) machinery, as well as ESCRT-independent pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eRelease: The mature MVBs can follow one of two pathways:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eDegradation: Fusion with lysosomes leads to the degradation of their content.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eExocytosis: Fusion with the plasma membrane results in the release of ILVs into the extracellular space as exosomes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIsolation and Characterization: To study exosomes generated from Galactomyces candidum, they need to be isolated and characterized:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIsolation: Common methods include differential ultracentrifugation, density gradient centrifugation, size exclusion chromatography, and immunoaffinity capture.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eCharacterization: Techniques such as nanoparticle tracking analysis (NTA), dynamic light scattering (DLS), electron microscopy (EM), and various biochemical assays (e.g., Western blotting for exosome markers) are used to characterize exosomes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eApplications: Exosomes from Galactomyces candidum have potential applications in various fields, including:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eTherapeutics: Due to their role in cell communication, they can be harnessed for drug delivery and regenerative medicine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eDiagnostics: Exosomes carry molecular signatures of their parent cells, making them useful biomarkers for disease diagnosis and monitoring.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003ca href=\"https:\/\/campsite.bio\/novaskinmedidermik\"\u003e\u003cspan\u003eNovaSkin \u0026amp; MediDermik\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eBrilliance Exosome\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Nova Skin Medidermik","offers":[{"title":"Default Title","offer_id":45243739635942,"sku":"mkexobrilliance","price":165.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/Brilliance_Exosome_Dermik_-_Nova_Skin_Medidermik.webp?v=1764018234"},{"product_id":"brilliance-1500-exosome-dermik","title":"Brilliance 1500 Exosome Dermik Lyophilized","description":"\u003cp\u003e\u003cstrong\u003eBrilliance 1500 Exosome Dermik\u003c\/strong\u003e (5 vials) (1,500 IU lyophilized per vial) helps improve the appearance of \u003ca href=\"https:\/\/novaskin.care\/collections\/hyperpigmentation\"\u003ehyperpigmented \u003c\/a\u003eskin such as melasma, chloasma, PIH, uneven tone, lentigo, freckles, and sunspots.\u003c\/p\u003e\n\u003ch2\u003ePresentation\u003c\/h2\u003e\n\u003cp\u003e5 vials with 1,500 IU Lyophilized Exosomes per vial.  Must reconstitute with sterile saline.\u003c\/p\u003e\n\u003ch2\u003eIndications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eMelasma\u003c\/li\u003e\n\u003cli\u003eChloasma,\u003c\/li\u003e\n\u003cli\u003ePIH\u003c\/li\u003e\n\u003cli\u003eUneven tone\u003c\/li\u003e\n\u003cli\u003eLentigo\u003c\/li\u003e\n\u003cli\u003eFreckles\u003c\/li\u003e\n\u003cli\u003eSun spots\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eHow to Use\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eBrilliance 1,500 Exosome Dermik\u003c\/strong\u003e must be reconstituted with sterile saline solution and can be applied by means of:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMicroNeedling with dermapen\u003c\/li\u003e\n\u003cli\u003eVirtual Mesotherapy with Electroporation\u003c\/li\u003e\n\u003cli\u003eIontophoresis (Galvanic Current)\u003c\/li\u003e\n\u003cli\u003eTopical Application\u003c\/li\u003e\n\u003cli\u003ePost-Peeling Topical Application\u003c\/li\u003e\n\u003cli\u003ePost-Microdermabrasion\u003c\/li\u003e\n\u003cli\u003eTopical Application with massage.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eIngredients (Lyophilized)\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus Extracellular Vesicles\u003c\/li\u003e\n\u003cli\u003eGalactomyces Extracellular Vesicles\u003c\/li\u003e\n\u003cli\u003eTranexamic Acid \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eBrilliance 1,500 Exosome Dermik\u003c\/strong\u003e is designed to promote the brightening of the skin with hyperpigmentation issues such as melasma, age spots, lentigo, chloasma, sun spots, and uneven skin tone mediated by the following tranexamic acid mechanisms:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cu\u003eTyrosinase Inhibition\u003c\/u\u003e:\u003cbr\u003eReduction of Melanin Production: Tranexamic acid inhibits the activity of the enzyme tyrosinase, which is crucial in melanin production, the pigment responsible for skin color. By reducing this enzyme’s activity, melanin production decreases, helping to lighten dark spots and hyperpigmentation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cu\u003eModulation of Growth Factors\u003c\/u\u003e:\u003cbr\u003eReduction of Melanocyte Growth Factors: Tranexamic acid can reduce the release of growth factors that stimulate melanocyte activity (the cells that produce melanin).\u003c\/li\u003e\n\u003cli\u003e\n\u003cu\u003eEffect on Keratinocytes\u003c\/u\u003e:\u003cbr\u003eBlocking Melanin Transfer: In addition to inhibiting melanin production, tranexamic acid can interfere with the transfer of melanin from melanocytes to keratinocytes (skin cells), resulting in less pigment accumulation on the skin’s surface.\u003c\/li\u003e\n\u003cli\u003e\n\u003cu\u003eSynergistic Effect with Other Treatments\u003c\/u\u003e:\u003cbr\u003eEnhancement of Other Depigmenting Agents: When combined with other depigmenting agents such as Vitamin C 20% Dermik, Glutathione Dermik, niacinamide, or kojic acid, tranexamic acid enhances their effectiveness.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eBrilliance Exosome Dermik\u003c\/strong\u003e are tiny, membrane-bound extracellular vesicles secreted by cells that play a crucial role in cell-to-cell communication. Exosomes may contain various bioactive molecules, such as tranexamic acid, proteins, lipids, RNA, and DNA, which can influence cellular processes:\u003c\/p\u003e\n\u003cp\u003eAnti-Aging Effect: Exosomes in general are believed to stimulate collagen production and improve skin elasticity, reducing the appearance of fine lines and wrinkles. \u003c\/p\u003e\n\u003cp\u003eRegeneration: They can promote the repair and regeneration of damaged skin cells, aiding in wound healing and improving skin texture.\u003c\/p\u003e\n\u003cp\u003eHydration and Brightening: By enhancing cellular communication, exosomes can contribute to improved skin hydration and a more even skin tone.\u003c\/p\u003e\n\u003cp\u003eWhen applied to the skin, exosomes can penetrate the outer layers and deliver their cargo to skin cells, thereby modulating cellular functions and promoting skin health.\u003c\/p\u003e\n\u003cp\u003eExosomes provide a highly effective and versatile delivery system for bioactive compounds, offering advantages in terms of biocompatibility, targeted delivery, protection of cargo, and efficient cellular uptake. These characteristics make them particularly valuable in both therapeutic and cosmetic applications.\u003c\/p\u003e\n\u003cp\u003eBiogenesis: Exosome biogenesis in Galactomyces candidum, as in other cells, occurs through the endosomal pathway:\u003c\/p\u003e\n\u003cp\u003eEndocytosis: The cell membrane invaginates to form early endosomes.\u003c\/p\u003e\n\u003cp\u003eMaturation: Early endosomes mature into late endosomes, also known as multivesicular bodies (MVBs). During this process, inward budding of the endosomal membrane occurs, resulting in the formation of intraluminal vesicles (ILVs) within the MVBs.\u003c\/p\u003e\n\u003cp\u003eCargo Sorting: Specific bioactive compounds, peptides, proteins, lipids, and nucleic acids are selectively incorporated into these ILVs. The sorting mechanisms involve several protein complexes, including the endosomal sorting complexes required for transport (ESCRT) machinery, as well as ESCRT-independent pathways.\u003c\/p\u003e\n\u003cp\u003eRelease: The mature MVBs can follow one of two pathways:\u003c\/p\u003e\n\u003cp\u003eDegradation: Fusion with lysosomes leads to the degradation of their content.\u003c\/p\u003e\n\u003cp\u003eExocytosis: Fusion with the plasma membrane results in the release of ILVs into the extracellular space as exosomes.\u003c\/p\u003e\n\u003cp\u003eIsolation and Characterization: To study exosomes generated from Galactomyces candidum, they need to be isolated and characterized:\u003c\/p\u003e\n\u003cp\u003eIsolation: Common methods include differential ultracentrifugation, density gradient centrifugation, size exclusion chromatography, and immunoaffinity capture.\u003c\/p\u003e\n\u003cp\u003eCharacterization: Techniques such as nanoparticle tracking analysis (NTA), dynamic light scattering (DLS), electron microscopy (EM), and various biochemical assays (e.g., Western blotting for exosome markers) are used to characterize exosomes.\u003c\/p\u003e\n\u003cp\u003eApplications: Exosomes from Galactomyces candidum have potential applications in various fields, including:\u003c\/p\u003e\n\u003cp\u003eTherapeutics: Due to their role in cell communication, they can be harnessed for drug delivery and regenerative medicine.\u003c\/p\u003e\n\u003cp\u003eDiagnostics: Exosomes carry molecular signatures of their parent cells, making them useful biomarkers for disease diagnosis and monitoring.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/novaskin.care\/\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eBrilliance 1500\u003c\/h2\u003e","brand":"Nova Skin Medidermik","offers":[{"title":"Default Title","offer_id":45682416615654,"sku":"mkbrillianceexo1500","price":299.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/Brilliance1500dermik.webp?v=1764053717"},{"product_id":"melano-fade-dermik","title":"Melano Fade Dermik","description":"\u003cp data-start=\"929\" data-end=\"1240\"\u003e\u003cstrong data-start=\"929\" data-end=\"951\"\u003eMelano Fade Dermik\u003c\/strong\u003e\u003cbr data-start=\"951\" data-end=\"954\"\u003eA professional skincare solution designed to help improve the look of uneven skin tone and visible hyperpigmentation. With a powerful blend of Tranexamic Acid, Vitamin C, Niacinamide (Vit B3), and Acetyl Glucosamine, this formula supports a brighter, more radiant complexion.\u003c\/p\u003e\n\u003cp data-start=\"1242\" data-end=\"1256\"\u003e\u003cstrong data-start=\"1242\" data-end=\"1254\"\u003eBenefits\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"1259\" data-end=\"1314\"\u003eHelps reduce the look of dark spots and discoloration\u003c\/li\u003e\n\u003cli data-start=\"1317\" data-end=\"1357\"\u003eSupports a more even-looking skin tone\u003c\/li\u003e\n\u003cli data-start=\"1360\" data-end=\"1394\"\u003ePromotes brightness and radiance\u003c\/li\u003e\n\u003cli data-start=\"1397\" data-end=\"1435\"\u003eRevitalizes dull, tired-looking skin\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"1437\" data-end=\"1470\"\u003e\u003cstrong data-start=\"1437\" data-end=\"1468\"\u003eSuggested Professional Uses\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"1473\" data-end=\"1515\"\u003eVirtual Mesotherapy with Electroporation\u003c\/li\u003e\n\u003cli data-start=\"1518\" data-end=\"1552\"\u003eIontophoresis (Galvanic Current)\u003c\/li\u003e\n\u003cli data-start=\"1555\" data-end=\"1597\"\u003eMicroneedling (dermapen or dermarollers)\u003c\/li\u003e\n\u003cli data-start=\"1600\" data-end=\"1657\"\u003eTopical application post-peel or post-microdermabrasion\u003c\/li\u003e\n\u003cli data-start=\"1660\" data-end=\"1686\"\u003eApplication with massage\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"1688\" data-end=\"1712\"\u003e\u003cstrong data-start=\"1688\" data-end=\"1710\"\u003eActive Ingredients\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"1715\" data-end=\"1732\"\u003eTranexamic Acid\u003c\/li\u003e\n\u003cli data-start=\"1735\" data-end=\"1770\"\u003eNiacinamide (Vitamin B3)\u003c\/li\u003e\n\u003cli data-start=\"1773\" data-end=\"1800\"\u003eVitamin C (Ascorbic Acid)\u003c\/li\u003e\n\u003cli data-start=\"1803\" data-end=\"1831\"\u003eN-Acetyl Glucosamine (NAG)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"1833\" data-end=\"1868\"\u003e\u003cstrong data-start=\"1833\" data-end=\"1842\"\u003eBrand\u003c\/strong\u003e\u003cbr data-start=\"1842\" data-end=\"1845\"\u003e\u003ca href=\"https:\/\/novaskin.care\/products\/melano-fade-dermik\"\u003eNovaSkin \u0026amp; MediDermik\u003c\/a\u003e\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":45831984644326,"sku":"mkmelano","price":179.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0703\/2678\/0134\/files\/MelanoDermik.webp?v=1770084628"}],"url":"https:\/\/www.novaskin.care\/collections\/may-2026-20-discount-collection.oembed","provider":"Nova Skin Medidermik","version":"1.0","type":"link"}